Increased diameter of hair shafts in 12-week-old VEGF transgenic mice (VEGF TG) during late anagen, as compared with wild-type (WT) littermates. ( a) Light microscopy of unstained plucked awl hair; scale bar = 30 μm. ( b) Quantitative analysis of hair shafts, measured at the level of their greatest width, revealed a significantly increased hair diameter in VEGF transgenic mice. Data are expressed as means ± SD ( n = 50 for each genotype). A P < 0.001, two-sided unpaired Student’s t test.
Yano K., Brown L.F., Detmar M., Control of hair growth and follicle size by VEGF-mediated angiogenesis. Clinical Investigation, 2001.