《Journal of Plastic Dermatology》近期發佈的一項全新研究再次確認，胸腺胜肽對治療脫髮具有效果。休止期脫髮 (TE) 和雄性禿脫髮 (AGA) 是導致脫髮的兩個主要原因。目前的研究表明，合成型胸腺胜肽經證實對AGA和慢性TE均具有臨床效果。
該調查的目標是檢驗低分子量胸腺胜肽（GKL factor）在為期6個月中對第一階段 AGA 和 TE 的療效與美容程度，採用的是胸腺胜肽與其洗髮精。這項研究在364名慢性 TE 和第一階段 AGA 男女病人中進行。
The treatment schedule was as follows:
- serum: once a day application for a total period of treatment of 24 weeks; (GKL一天一次，為期24周)
- shampoo: three times/week during the study period of 24 weeks.(洗髮精一周三次，為期24周)
All the subjects underwent pull test, evaluation of symptoms (seborrhea, erythema and pruritus).Tolerability and cosmetic acceptance/tolerance were evaluated after 180 days of treatment.
Men: In AGA patients the improvement of pull test has been of 94% with a mean symptoms improvement of 89%; In TE patients the improvement of pull test has been of 98% with a mean symptoms improvement of 77%.
Women: In AGA patients the improvement of pull test has been of 98% with a mean symptoms improvement of 95%; In TE patients the improvement of pull test has been of 99% with a mean symptoms improvement of 95%.
In all groups the tolerability was referred as positive in 100% of cases and no side effects were recorded. The cosmetic acceptance/tolerance was also referred as positive in 98% of the cases.
In conclusion, synthetic thymus peptides showed significant efficacy and tolerability in the clinical treatment of initial AGA and chronic TE in men and women after a six month-treatment.
- Barbareschi M, Arena N et al.: Multicentric study of the effects of topical lotion and shampoo containing synthetic thymus peptides on androgenetic alopecia and chronic telogen effluvium in women and men. Journal of Plastic Dermatology. 2013: Vol.9 (2),
 N. Meier: Thymic Peptides Differentially Modulate Human Hair Follicle Growth. Journal of Investigative Dermatology (2012)
 Donne Dermatologhe Italia (DDI). Clinical Investigation of the effects of topical lotion and shampoo containing synthetic thymus peptides on androgenetic and chronic telogen effluvium in women. J Plastic Dermatol 2008; 4:199-205
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